As technological advancements around microbiological testing continue to grow within the pharmaceutical industry, USP’s Microbiology Expert Committee seeks to update some of its microbiology chapters. For each five-year cycle, the Expert Committee has an established workplan intended to help meet USP’s standards-setting goals. Some of the workplan’s major initiatives in the current USP cycle (2015–2020) include sterilization processes and sterility assurance, parametric release, depyrogenation, endotoxin testing, rapid sterility testing of short-life products and a test for the presence of Burkholderia cepacia complex.