Are the Components in Your Prefilled Syringes Compatible?
Prefilled syringes offer potential
cost savings for high-value, complex,
biologic products because
minimal overfill volume is needed in
the primary container as compared to
vials (1). While a prefilled syringe offers
many advantages for biologic products,
manufacturers must carefully evaluate
the potential impact of a prefilled
syringe on product quality by conducting
laboratory studies prior to selecting the
final components. In particular, assessing
the impact of silicone oil and tungsten
residues is crucial.