PDA Letter Article

New Approach Suggests Continuous Lyophilization is Possible

by Pieter-Jan Van Bockstal, Ghent University, Jos Corver, RheaVita, and Thomas De Beer, Ghent University

Conventional batch freeze-drying has long been the mainstay for stabilizing biologic drug products in storage and distribution, but it presents many challenges. An innovative continuous process for freeze-drying has been developed, however, that may offer a view of the future of freeze-drying for biologics.