Skip To The Main Content

PDA 120.1 Foreign Particulate Examination, Isolation and Analysis

Nov 08 - Nov 09, 2022
1:30 PM
-
4:30 PM
| W. Europe Standard Time
Online
  • Virtual
  • Education
  • Online
Register Now

Overview

This live eLearning training course will cover the analytical approach and methods used in foreign particulate examination, isolation and analysis. The training course will consist of both lecture and demonstrations with an emphasis on the practical laboratory exercises. Participants will understand what foreign particulate is and why it is important to identify its composition and potential sources. Three analytical techniques will be covered - polarized light microscopy, infrared spectroscopy/confocal Raman microscopy and scanning electron microscopy. The advantages and disadvantages of each technique for particulate analysis will be demonstrated to understand why using multiple complementary techniques is often the best approach.

Attendees will observe sample preparation, sample analysis and participate in data interpretation. At the completion of the training course, participants will have observed particle isolation and handling, and be able to explain the analytical methods used in identifying particulate matter.

For more options and/or related training courses, please visit the page(s) below.

PDA Visual Inspection Training Courses

Agenda

  • Day 1
  • Day 2

  • Welcome (15 min)

    Introduction to Foreign Particulates - Lecture (30 min)

    Inspection, Documentation, and Particle Isolation - Lecture and Demo (45 min)

    Break (10 min)

    PLM, SEM and FTIR/CRM Analysis - Lecture and Demo (60 min)

    Case Studies - Lecture and Activity (20 min)

  • Recap Day 1 (10 min)

    Unknown Sample: Inspection - Demo and Activity (30 min)

    Unknown Sample: Filtration and Isolation - Demo and Activity (30 min)

    Break (10 min)

    Unknown Sample: Particle Preparation and Analysis - Demo and Activity (80 min)

    Summary of Analyses and Particle Identification - Lecture (20 min)

Trainers

Richard S. Brown
Richard S. Brown
MVA Scientific Consultants, Inc.
Bio
Richard S. Brown
MVA Scientific Consultants, Inc.

Mr. Brown is a forensic microscopist with over 30 years’ experience in the characterization of small particles using light and electron microscopy. Mr. Brown's expertise focuses on method development and foreign particulate isolation and analysis in the aerospace, manufacturing, pharmaceutical and medical device industries. Mr. Brown joined MVA in 1991 and holds an M.S. in Forensic Chemistry from Northeastern University in Boston, MA, and is a diplomat of the American Board of Criminalistics.
Jose Del Rio
Jose Del Rio
MVA Scientific Consultants, Inc.
Bio
Jose Del Rio
MVA Scientific Consultants, Inc.

Jose Del Rio has nine years of experience in microanalysis, specializing in submicron particle isolation and sample preparation in a clean environment. He is skilled in the use of scanning electron microscopy-energy dispersive x-ray spectrometry (SEM-EDS) and optical microscopy, including reflected/transmitted light, brightfield/darkfield, and polarized light microscopy, in the identification of particulate. Jose is also trained in the characterization of organic materials utilizing infrared spectroscopy.
Casey Jarvis
Casey Jarvis
MVA Scientific Consultants
Bio
Casey Jarvis
MVA Scientific Consultants

Casey Jarvis received her B.S. in Chemistry from West Georgia University in Carrollton, GA. After her Bachelor’s degree, she worked as a Research Scientist at MVA Scientific Consultants in Duluth, GA. After one year at MVA Scientific Consultants, Casey pursued a graduate degree and received her M.P.S. degree in Forensic Science at the Pennsylvania State University. Casey returned to MVA Scientific Consultants after graduate school and works with a variety of microscopes, using characterization techniques to investigate foreign material in products and packaging. She specializes in Fourier Transform infrared spectroscopy (FTIR) and confocal Raman microscopy (CRM). Casey has experience in light microscopy, polarized light microscopy (PLM), scanning electron microscopy (SEM), hot stage microscopy, chemical microscopy, photomicrography, surface roughness analysis, and image processing and analysis. She also has experience in small particle isolation and sample preparation in a clean room.

Learning Objectives

  1. Describe handling and manipulation of small particles
  2. Describe preparation of samples for PLM, FTIR/CRM and SEM
  3. Describe operation of different analytical tools for particle analysis
  4. Evaluate different analytical methods for particle analysis
  5. List the tools and equipment needed to set up a particle analysis lab

Who Should Attend

This training course is intended for professionals who are involved in particulate related issues in sterile drug manufacturing.

Departments
  • Quality Control (Analytical)
  • Manufacturing
  • Quality Assurance Operations
  • Validation

Roles
  • Analyst
  • Specialist
  • Supervisor
  • Manager

Registration Fees

Register Now
Registration Type Price
All Participants €600

Got a Question? We have answers

Contact Us
Become a Sponsor

Interested in becoming a sponsor? Learn about opportunities and benefits.

Request Information

Media Partners

PDA Members Save Substantially