Filtration is the process of separating unwanted contaminants, both viable and non-viable, from fluid streams and has become the prevalent sterilization method due to the increase in bioprocess applications. The filter can be a protective unit to prolong the life of other equipment, to reduce the amount of bioburdens, or to act as the last critical barrier before the product reaches the vial. The criticality of the performance of the filtration steps shall not be underestimated but require in-depth knowledge to run the filtration processes in a robust and optimal manner. This highly interactive training course is intended to provide a comprehensive understanding of pharmaceutical/biopharmaceutical liquid filtrations processes.
Topics to be addressed include:
- Filter manufacturing and construction of membranes, pre- and depth filter construction
- Structural and design features of filters
- Contaminant retention including mechanisms for liquid filtrations, e.g. sieve retentions, adsorptive sequestration, and other mechanisms
- Liquid applications – points to consider
The training course format will be lecture with a question and answer session following the presentation. The trainer will be available to respond to participant issues during and after the formal training sessions.