PDA Technical Report No. 71 (TR 71) Emerging Methods for Virus Detection (single user digital version)

Aug 2015
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Technical Report No. 71, Emerging Methods for Virus Detection describes and critically assesses methods currently used for the detection of potential adventitious viruses in biomedicinal products and their production processes. It also details new methods that have emerged as a result of technological advances in molecular biology, mass spectrometry and genomics, all of which offer the potential for novel virus detection opportunities.

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Table of Contents

Table of Contents:

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  1. Introduction
  2. Glossary of Terms
  3. Conventional Virus Detection Methods
  4. The Need for New Technologies for Virus Detection
  5. Degenerate and Consensus PCR Assays
  6. Broad-Range PCR with Electrospray Ionization Mass Spectrometry (PCR/ESI-MS)
  7. Massively Parallel Sequencing
  8. Broad-Spectrum Microbial Detection Microarrays
  9. General Considerations and Summary
  10. Conclusion
  11. References

Figures and Tables Index