Below are the top ten articles from the PDA Journal of Pharmaceutical Science and Technology for the month of April.

1. PQRI Special Section – Research

Dennis Jenke, et al., “Extractables Characterization for Five Materials of Construction Representative of Packaging Systems Used for Parenteral and Ophthalmic Drug Products” September/October 2013

2. Research

Dennis Jenke, et al., “Simulated Leaching (Migration) Study for a Model ContainerClosure System Applicable to Parenteral and Ophthalmic Drug Products” March/April 2017

3. PDA Paper

Stan Bukofzer, et al., “Industry Perspective on the Medical Risk of Visible Particles in Injectable Drug Products” January/February 2015

4. PQRI Special Section – Review

Diane Paskiet, et al., “The Product Quality Research Institute (PQRI) Leachables and Extractables Working Group Initiatives for Parenteral and Ophthalmic Drug Product (PODP)” September/October 2013

5. PDA Paper

Emma Ramnarine, et al., “PDA Points To Consider: Technical Product Lifecycle Management: Communication and Knowledge Exchange between Marketing Authorization Holders and Health Authorities” March/ April 2017

6. Review

Stephen E. Langille, “Particulate Matter in Injectable Drug Products” May/June 2013

7. Research

Paul Flaya, James D. Stamey, and John W. Seaman, Jr., “A Bayesian Approach to Determination of F, D, and Z Values Used in Steam Sterilization Validation” March/April 2017

8. Research

Julie Wang, et al., “Mycoplasma Clearance and Risk Analysis in a Model Bioprocess” March/April 2017

9. Conference Proceeding

George Miesegaes, “Viral Clearance by Traditional Operations with Significant Knowledge Gaps (Session II): Cation Exchange Chromatography (CEX) and Detergent Inactivation” January/February 2014

10. Technology/Application

Eric C. Hilario, et al., “An Improved Method of Predicting Extinction Coefficients for the Determination of Protein Concentration” March/April 2017