Skip To The Main Content

PDA EU00171 Optimize Your Freeze-drying Process

Sep 15, 2021
Berlin, Germany

  • Education
  • Europe

left to register

Note   COVID-19 situation up-date 30th March 2020:

PDA is closely monitoring the Corona virus situation. 

Should an event need to be postponed or cancelled, PDA will send email updates to all participants with additional details and information.

If you have any immediate questions or requests, please contact [email protected]. Additionally, you may visit the PDA official statement on our website.


A successfully optimized freeze-drying cycle will provide reliable, safe processing in an efficient manner. Each stage of the process – freezing, primary drying and secondary drying – poses its own challenges. Many factors influence the design of the cycle, including the specific thermal characteristics of the product, the type and amount of product per batch or container, and the capabilities of the processing equipment to be used.  

This training course provides an overview of how to develop an optimized freeze-drying process. It will go through each critical stage required to optimize a cycle including: an overview of the freeze drying process, formulation design of freeze dried products, characterization of the formulation in the frozen state prior to freeze drying, and cycle development, including the iterative approach, and the use of PAT (Process Analytical Technology) for monitoring the process. 



  • 9:00
    Welcome, Opening Remarks and Introductions

    Introduction to Freeze-Drying

    Factors Effecting the Rate of Sublimation

    Coffee Break

    Typical CQAs and Excipients in Freeze Dried Products

    Frozen State Characterization

    Lunch Break

    Overview of Process Analytical Technology Used in Monitoring Primary Drying

    Cycle Development and Scale Up: Use of the Iterative Approach

    Coffee Break

    Cycle Development and Scale up: Use of the Iterative Approach

    Round-up Discussion and Questions

    End of Course


Andrew Bright
Andrew Bright

Additional Information

  • Learning Objectives

    Learning Objectives

    • Gain a basic understanding of the freeze-drying process, together with the factors that influence the product and process. 
    • Characterization to determine a product critical temperature prior to freeze-drying. 
    • Review formulation development to gain understanding of typical excipients and their purpose in a formulation. 
    • Learn about typical CQAs in freeze dried products, what factors influence these attributes, and methods of monitoring and controlling attributes.  
    • Learn how to develop a freeze-drying process using the traditional iterative (stepwise) approach and how this compares to the use of SMART software. 
    • Gain a basic understanding of typical Process Analytical Technology (PAT) to monitor the freeze-drying process and when primary drying is complete. 


  • Who Should Attend

    Who Should Attend

    • R&D Scientists
    • Formulation Scientists
    • Product & Process Scientists/ Managers
    • Quality Control Departments

Got a Question? We have answers

Contact Us


PLEASE READ  PDA is not affiliated or contracted with any outside hotel contracting company. If someone other than PDA or the PDA chosen hotel contacts you suggesting that they represent any PDA event, they do not. It is PDA's recommendation that you book your hotel directly through the official PDA chosen hotel that is listed on our web site.

Berlin, Germany

How to Get Here

By Air

More information coming soon.

By Car

More information coming soon.

Other Options

More information coming soon.


Registration Fees

Regular Price
Registration Type Price
All Participants € 895

* For this member type or discount, online registration is not available, please contact [email protected].

Group Registration Discount: Register 3 people from the same organization as a group (at the same time) for the event and receive the 4th registration free. Other discounts cannot be applied.

GENERAL TERMS AND CONDITIONS: PDA will send you a confirmation letter within one week of payment being received. You must have this confirmation letter to be considered enrolled in a PDA event. If you have submitted a purchase order or requested an invoice, please be advised that a credit card guarantee is needed. PDA reserves the right to modify the material or speakers/trainers without notice or to cancel an event. If an event is cancelled, registrants will be notified by PDA immediately and will receive a credit (registration fee paid). PDA will not be responsible for any costs incurred by registrants due to cancellation. Please note that the attendee list is shared with attendees, trainers, and exhibitors and may be used to follow up on specific areas of interest after the event. Video, photo, and audio recordings are prohibited at all PDA events.

CANCELLATION: If a cancellation request is received 30 days before the event, a credit (registration fee paid minus a 200.00 USD/EUR processing fee) will be given. No credits will be given for cancellation requests received less than 30 days before the event. Cancellation requests must be emailed to [email protected].


Become a Sponsor

Interested in becoming a sponsor? Learn about opportunities and benefits.

Request Information


Attendee List Email Scam

Unfortunately, emails are circulating that offer to sell attendee lists for many of PDA’s conferences and events. These emails are sent by scammers.

Note: PDA does not sell its exhibitor or attendee lists, and no third-party is authorized to distribute or sell any lists related to our events. Statements claiming to offer our attendee lists are fraudulent. If you receive emails that propose to sell PDA conference attendee lists, do not engage with the sender and delete the message immediately.

Become an Exhibitor

Interested in becoming an exhibitor? Learn about opportunities and benefits.

Request Information

Media Partners


Program Inquiries
Exhibition Inquiries
Training Course Inquiries

Tel: +1 (301) 656-5900
[email protected]

Tel: +49 (0) 30 43 655 08-10

Registration Customer Care

Tel: +1 (301) 656-5900 ext. 115
[email protected]

PDA Members Save Substantially