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2020 Freeze Drying

Development of a Freeze Drying Process

Sep 22 - Sep 23, 2020
Dublin, Ireland

  • Education
  • Europe

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Program Highlights
Bring your own samples for discussion.


This workshop will give a thorough introduction into the Physics and Thermodynamics of Freeze-Drying. It comes with an additional overview about technical aspects to be considered and gives an overview about current technologies available on the market. It is created to introduce all people who are professionally linked to Freeze-Drying and might be of special interest for cycle developers (R&D), upscale & transfer specialists, project managers & engineers, process & site engineers, qualification & validation specialists. Open problem examination allows you to bring in a current problem linked to Freeze-Drying. The group will discuss and evaluate possible approaches for troubleshooting.


  • Day 1
  • Day 2
  • Tuesday, 22 September 2020



    • Introduction to Drying Technologies
    • Overview of the Freeze Drying Process
    • Properties of Water
    • Properties of Heat Transfer during Lyophilization

    Nucleation (with Parallel Hands-on)

    • Scientific Basics
    • Freezing Process
    • Sensors & PAT

    Coffee Break

    Nucleation (Cont.)

    • Hands-on: Freezing of Sucrose in a Lyo with integrated thermo-resistant measurement

    Lunch Break


    • Scientific Basics
    • Drying Process
    • Sensors & PAT
    • Hands-on: Ice-temperature calculation based on manometric temperature measurement

    Coffee Break


    • Scientific Basics
    • Residual Moisture
    • Sensors & PAT
    • Hands-on: Preparation and start of a lyo-process

    Bring in your Questions: Real problems of Freeze Drying can be presented and will be discussed in the group

    End of Day 1

  • Wednesday, 23 September 2020


    Repetition of Previous Day Theory

    Hands-On: Recipe Development

    Coffee Break

    Process Design
    Derive design requirements from process requirements

    • Process requirements
    • Process steps of Lyo-cycle
    • Auxiliary processes for parenteral production

    Lunch Break

    Design of a Lyophilizer - From Engineering to Qualification

    • Vessel system
      • Shelf system
      • Chamber system
      • Condenser system)
    • CIP / SIP-Equipment
    • Qualification procedures
      • CIP-Process
      • SIP-Process
      • Leak Test

    Auxiliary Systems of a Lyophilzer

    • Aeration System with Filter test
    • Sensor Equipment / PAT Methods
    • Vacuum System
    • Heat Transfer System

    Coffee Break


    • Evaluation of the Lyo experiment & samples of collapsed probe

    End of Training Course


Georg  Frinke
Georg Frinke

Additional Information

  • Learning Objectives

    Learning Objectives

    Upon completion of this course participants will know the basic principles of all Freeze Drying aspects:
    • Physical / Thermodynamic Theory of Nucleation, Sublimation and Desorption
    • Technical & Technological Solutions to accomplish a standard process
    • Based on the prior theory, several hands-on-sessions provide practical knowledge to design a Freeze-Drying process
    • Basics of qualification of a freeze dryer
  • Who Should Attend

    Who Should Attend

    This course is designed specifically for:

    • Cycle Developers (R&D)
    • Upscale & Transfer Specialists
    • Project Managers & Engineers
    • Process & Site Engineers
    • Qualification & Validation Specialists
    • Members of Parenteral Production Teams

Got a Question? We have answers

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PLEASE READ  PDA is not affiliated or contracted with any outside hotel contracting company. If someone other than PDA or the PDA chosen hotel contacts you suggesting that they represent any PDA event, they do not. It is PDA's recommendation that you book your hotel directly through the official PDA chosen hotel that is listed on our web site.

Crowne Plaza Dublin Airport

Northwood Park
Dublin, Ireland
Phone: +353 1 862 8888

Crowne Plaza Dublin Airport
  • Accommodations

    Hotel Nearby
    PDA Europe recommends the reservation at one of the following hotel.
    The general terms of business are valid at the event hotels.

    Crowne Plaza Dublin Airport
    Northwood Park
    Santry Demesne
    Dublin 9

    The hotel is a 5-minute drive from Dublin Airport, with a free shuttle to and from the airport. It has luxurious rooms, free internet and good bus links to the city centre.
    Each bedroom has air conditioning, an on-demand movie system, a safe and ironing facility.Crowne Plaza Dublin Northwood is set in parkland, close to the M1 and M50, and 15 minutes from Dublin city centre.

    Northwood Crowne Plaza has a coffee bar, the Cinnabar Red Bar and a Californian-Asian restaurant, for a great variety of food and drinks. Breakfast starts early at 06:00. Crowne Plaza Northwood offers a park and fly facility and is on the airport bus route. Omni Shopping Centre, Swords Pavillions, Movie Plex and Northwood Business Campus are nearby. Croke Park Stadium is a short drive away.

    PDA Europe has reserved a limited number of rooms until the 24th July 2020
    Book your room for the PDA Group Rate

    • Single Superior Room € 159 per night*
    • Double Superior Room € 189 per night*

    *Rates are per room and night, including the following services and benefits free of charge:

    • Buffet Breakfast in the restaurant
    • Wireless Internet Connection (WI-FI)
    • VAT, Taxes and Service Charge will apply
  • Amenities

How to Get Here

By Air

Nearest Airport:

Dublin Airport - DUB
Airport Phone: +353 1 814 1111
9km , 10 min by car
Free Shuttle Bus fom and to the Hotels

By Car

The hotel is almost 10km away from the Dublin Airport.

Other Options

More information coming soon.


Registration Fees

Regular Price
Registration Type Price
All Participants €1595

All fees given in Euro, excluding VAT (23%)

* For Government/Health Authority/Academic nonmembers, online registration is not available and must be faxed in.

All rates in US dollars. To receive the prevailing rate, PDA must receive your registration(s) by 5:00 p.m. ET on or before the date noted.

Special Dietary Requirements

If you require special accommodations and/or have special dietary requirements, please state them in the appropriate field when you register for the event(s).

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SUBSTITUTION: If a substitution request is sent 30 days before the event, no fee will be charged. After this period, a $200 fee will be charged. If you are a non-member substituting for a member, you will be required to pay the difference of the non-member fee.

REFUND: If a refund request is sent 30 days before the event, a full refund will be given minus a $200 fee. After this period, no refunds will be given. Refund requests must either be faxed to + (301) 986-1093 or emailed to [email protected]. Phone messages are not accepted.


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